in power supplies I normally only use one ground (even if they speak about power ground and signal ground). However, I am careful about how I place components and how I route the signals - for example, I do not place sensitive components and tracks into High current area. The best is to find an evaluation board of that chip and check how the chip manufacturer designed the PCB. If they use two different grounds, you may want to do it the same way.
In case you decide to split GND, I would use two different netnames + a component to connect these two grounds together. You can use for example 0R (I have used this), a special VIA component (I have never used this) or Altium supports a special component called net-tie (I have never used it, but it looks like it could be what you are looking for): "a Net Tie component would be (however not limited to) connecting two polygons of differing ground nets together at a specific place (AGND and DGND for instance), " ... more ...
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